Theoretical Systems Biology

I am a second year PhD candidate working under the supervision of Dr. John Pinney, co-supervised by Prof. Michael Stumpf. I graduated with a first-class honours degree in Mathematics from University College London in 2008 going on to achieve an MSc in Bioinformatics and Systems Biology, with distinction, at Imperial College London in 2009.

My research is centred on attempting to model the evolution of protein interactions. The modelling combines sequence evolution on phylogenies with models of interaction gain and loss (re-wiring events) between proteins. These descriptions of interaction evolution can then be used to study how ancestral interactions evolved to present day, observable interactions and, in addition, can be used to make predictions in present day species for which we have no interaction data.